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Cancell™ like products, Cantron and Protocel, are safe alternative cancer treatments which have successfully treated people and animals for a wide array of diseases for more than thirty years without dangerous side effects. Not only is Protocel anti-cancer, it is also strongly anti-viral and one of the most powerful antioxidants ever tested.

On this web page you may see "Cancell" used interchangeably with "Protocel" in places where both Cantron and Protocel are discussed. Cantron and Protocel are brand names for Cancell, are produced by different companies, and have the same ingredients with slightly different ratios of those ingredients.

Other Diseases, AIDS, Herpes...

Protocel has been effective against viruses including AIDS, Herpes (see below), Chronic Fatigue syndrome, lupus, endimetriosis, Crohn's disease, fibromyalgia, almost all auto-immune disease, and has some success treating: ALS (Lou Gehrig's disease), Multiple Sclerosis, Muscular Dystrophy, Parkinson's, Alzheimer's, Leukemia, Rheumatoid Arthritis, and Scleroderma. Information about these diseases and Protocel will be added as I continue my research. I don't have any more information on the above diseases that don't have a link, please contact HOPE for more information.

The mechanism that that occurs when Protocel is given to an AIDS patient is that Protocel breaks down the cell that the virus has invaded. At that point the virus has lost its protection again allowing the body’s immune system to attack the virus. This results in an initial increase in viral count when the Protocel treatments start. There are not actually more viruses; they are just more detectable due to the removal of this protective layer. For more information or to take Protocel for AIDS, go to the Protocel Protocols for AIDS*.


Protocel has demonstrated strong anti-viral abilities against most viruses including colds and flu. It can be exceptionally helpful for people who take a long time to get rid of these common illnesses.


The book the Cancell Controversy by Louise Trull reports that 15 cases of herpes were treated with Cancell by physicians with positive cures in every case within 3 to 6 days. However, extensive follow ups were not performed. It is more likely that Protocel simple reduces the length of episodes. However, there is some chance that a long course of treatment, about four months, may make it very difficult for the virus to launch another episode or can greatly reduce the frequency of episodes.

Heart Disease and High Blood Pressure

Some people who have taken Protocel for cancer also had high blood pressure and clogged arteries. Since the cancer was more of a threat, these people ignored their heart conditions to concentrate on their cancer. After Protocel had corrected their cancer, they were surprised to learn that their blood pressure had gone back to normal. Some of these people had angiograms performed and found that the plaque in their arteries had been dissolved. For this reason the Protocel manufacturers recently (March 2003) performed tests on Protocel to determine its antioxidant abilities. The results of the tests indicated that Protocel is the most powerful antioxidant available. It is many times more powerful than any other antioxidant. For this reason Protocel is a life saver for people with high blood pressure because the current high blood pressure medication has a terrible list of side affects.


The first Cancell-like formula was called Entelev and was developed by a chemist, James Sheridan of Rosell, Michigan. Currently, the brand names Cantron and Protocel are used for Cancell. Although Sheridan was a researcher at the Michigan Cancer Center, Sheridan was not a medical doctor. This may be one of the reasons the medical profession has offered so much resistance to Cancell. There is even a name for this resistance: professorial blockade. Another reason for this resistance may be due to the fact that Cancell is not only anticancer it is also antiviral. It is also the most complete and the strongest antioxidant ever tested. Since his original formula the following names have been used: Sheridan's Formula, Jim's Juice, Crocinic Acid, JS-114, JS-101, 126-F, Entelev, Cancell, Cantron, and Protocel.

Sheridan theorized the possibility of chemically controlling the energy needed by the cells of our body to cause energy-low cancer cells to revert to a state where the body can eliminate them as foreign matter. The theory postulates that cancer cells are too low in energy to proceed with their normal development. Cancer cells stop their development just short of differentiating into a normal liver, lung, brain ... cell. Sheridan proposed to push cancer cells backward in their development instead of try to encourage them to differentiate as many cancer treatments attempt.

Sheridan believed he had found a method of controlling the energy available to cells in the early 1930s after witnessing a chemical reaction called rhythmic banding in an analytical chemistry laboratory at Carnegie Tech and reading the Debye Theory, published in 1927 which explores the effects of changing the dielectric constant on reactions of positive and negative ions suggested the means to accomplish this energy reduction.

About 1950, Sheridan was invited to join the staff of the Detroit Institute of Cancer Research. There he performed the required chemical work on the project and the institute experts performed the animal tests. In late 1953, the institute director concluded that Entelev was ready for a clinical program. A committee was formed consisting of the Dean of Medicine at Wayne University, three oncologists from area hospitals, and the director. The committee spent several days interviewing the experts who were running the tests, reviewed the test results and concluded that the material was ready for a clinical program. The director of the Detroit Institute of Cancer Research informed the American Cancer Society about the product. A meeting was requested to take place in New York City. The director and the Dean attended the meeting. They returned and reported that the American Cancer Society did not approve the test because Mr. Sheridan did not prove that he owned the idea. Sheridan was later fired.

Since Sheridan had worked on his idea for many years, it would be fairly easy to show that the idea was his, but Sheridan was fired. Why he was fired is not a mystery if you know how diabolical the pharmaceutical companies are. During the Nuremberg war crimes trials, executives of German pharmaceutical companies were the only civilians who received prison sentences. The descendent companies now operate world wide and receive great respect from the uninformed. An example of such a company is none other than Bayer the aspirin giant that many people think is an American company. These pharmaceutical companies control medical research by giving or withholding grants for research. Moss's book The Cancer Industry is full of such dirty dealing.

Ready for People

Based on the animal testing, Sheridan knew that Entelev was non-toxic and started giving it to friends who were at the “end of the line.” Word spread of the effects it had on these people and Sheridan started receiving requests from all over the country. Unable to refuse to give people a chance for life, he began distributing it for free to anyone who asked for it. The FDA eventually placed an illegal injunction against the distribution of Entelev. When Sheridan attempted to appeal the original court decision, the court claimed to have lost the transcript. A transcript must accompany any appeal application. Appeal application must be filed within 60 days of the original court decision. The transcript was located just after the 60 days.

Ed Sopcak Joins the Effort

Around 1984, a cancer sufferer (who wishes to remain nameless) was given the prognosis of six weeks to live due to advanced cancer. Instead of dying on schedule, he acquired a bottle of Entelev and in six weeks he was declared cancer-free. Unfortunately, Sheridan had recently quit distributing Entelev in response to a court injunction. This nameless man had written six technical books, and was competent to understand the formulation so Sheridan gave it to him, but he didn’t have the equipment for production. Mr. Nameless contacted a friend, Ed Sopcak who is a metallurgist. Sopcak agreed to make it and eventually started working with Sheridan and distributing it for free between 1984 and 1992.

The FDA Blockade

With their own money Sheridan and Sopcak continued to seek FDA approval. The FDA required toxicity testing. Sheridan and Sopcak decided to pay for this testing because they couldn’t get help from the drug company influenced cancer agencies. Sheridan found what he considered the best laboratory in the country in New Mexico. The cost of the toxicity test was originally $5,000. After they got the material, they called Sheridan and said it would cost $7,000. Sheridan and Sopcak still agreed. The cost went to $15,000. Still Sheridan and Sopcak agreed. Then the lab called and said for some reason or other they were unable to do it.

Sheridan drove to the lab and said he would like to have a toxicity test run. They said they could have it done within a week. After hearing that the material was Entelev, everything changed. They absolutely couldn't get around to doing it. This treatment continued for years. Some people would say that the $700 billion a year Chemo industry has something to do with this blockade. Eventually, Sheridan retired and no longer pursues the battle.


Although the ratio of ingredients of Cancell-like products has changed slightly over the years, the ingredients listed on the labels of Cantron and Protocel are: tetrahydroxyquinone, rhodizonic acid, sodium, potassium, croconic acid, catechol (or pyrocatechol), triquinoyl, leuconic acid, inositol, and copper. The Protocel label also lists "mineral and trace elements" which are at a level of no consequence.

The Formulation Change / Name Confusion / Reputation Destruction

Ed Sopcak worked with James Sheridan, the developer, by distributing Entelev (the original name for Cancell) under the name Cancell between 1984 and 1992. Sopcak's efforts and connections greatly increased public awareness of Cancell. For this reason the term Cancell is used most often when referring to Entelev. Around 1992 Sopcak changed the formulation completely. Sopcak’s new formula resembled a homeopathic product. He stated that it was distilled water “programmed vibrationally.” At this point Sopcak should have changed the name of the product he was manufacturing, but he continued to call it Cancell because he felt that both formulas worked the same way even though they were chemically as different as night and day. Entelev was a dark liquid. Sopcak's new formula was completely clear and contained none of the chemicals that Sheridan had specified. Eventually, Sopcak did change the name of his formula to Quantrol, but the damage to Cancell's reputation continued. This web page uses the term Cancell to refer to the dark formula.

Not long after the formulation change, Quantrol/Cancell received a lot of media attention. Sopcak promoted Quantrol on TV and in articles often referring to it as Cancell and created tremendous confusion. Suddenly, after distributing Cancell for eight years Sopcak was taken to court by the FDA creating more publicity for his "water" and making Cancell seem like a joke. With the wrong formula receiving this negative attention, Cancell's reputation was dealt a devastating blow.

Sopcak Gets Stopped but Distribution Continues

The courts stopped Sopcak from distributing either formula, but during that time a company in Florida started producing Entelev based on a formula forwarded by an intermediary. In 1984 Medical Research Products obtained the Entelev formula and started producing it under the name Cantron. In the spring of 2000 a Canadian company started working with the Sheridan family and called their product Protocel. So now there are two manufacturers. Both charge about the same price. Both products have the same ingredients which are the same as Entelev although there is a slight difference in the quantity of the ingredients.


The developer, James Sheridan felt that his formula was 50% effective (higher for brain tumors). The effectiveness was determined to be a bit lower for children. This seems to be related to the higher level of growth common in the cells of children.

The webmaster, Paul Winter documented case histories for four years. You can read case histories and a summary or the findings for the last year. This is when Protocel and Cantron were both available. Although this study is crude, the results agree with Sheridan's 50% number. Some supporters of Cancell claim 80% to 90% effectiveness. However, no documentation is available to support these numbers.

Cancers That Respond Poorly to Protocel

Protocel seems to be effect against all types of cancer and benign tumors; however, it does not perform well against the following:

  • Ovarian cancer

  • Internal melanomas

  • Desmoid tumors


Response Time

Different people respond at different speeds to Protocel. Some cancer sufferers notice response in a week and virus symptoms can go away in one day. However, it can take as much as three months or more for some cancer sufferers to notice improvement especially for Lymphomas. The lymph system has a very slow circulation rate. This slows down the action of Protocel. In the words of James Sheridan, "it takes time to work... 7 to 9 weeks is typical and some cases take up to 3 months or more to see a response."

One of the reasons for Protocel's apparent slow action is due to the time it takes a person's system to convert the tumors to waste matter and longer to recover from the damage the tumor produced. Often the waste matter around a tumor is misread by a doctor as tumor growth and a person stops taking Protocel before it is finished working. This tragedy is difficult to prevent.

How to tell if Protocel is working

When malignant cells go past the primitive state, they lyse or self-digest. When the malignant cells, self-digest, they change from cancer to waste material, composed of two amino acids that have the appearance of raw egg whites, which are mostly excreted through normal body waste disposal or in the case of lung cancer, this material is coughed up.

Tumor Markers

Tumor markers can rise for three to four months after taking Protocel. This does not mean that Protocel is not working.


No studies on Protocel have been published in standard scientific journals, and no clinical trials (research studies with people) of Protocel have been done.   

Conclusiveness of Papers

No scientific peer reviewed papers have been written on Protocel. However, the antioxidant test performed in 2003 verified the tremendous antioxidant ability of Protocel. The results of two independent laboratories are in: Protocel is by far the most powerful antioxidants thus far test. It is:

 Over 25 times more powerful than the previous best antioxidant¨ against peroxyl radicals.
 Over 45 times more powerful than the previous
best antioxidant against hydroxyl radicals.

These are the two most destructive and difficult to defeat free radicals. This makes Protocel (and Cantron) the only antioxidant that eliminates both of the most dangerous free radicals. Protocel also blocked the formation of all superoxide radicals in the test system.

Standalone Ability

Protocel can be taken without any additional supplements and still be effective. However, the addition of the following supplements are recommended by one or other of the manufacturers to support the action of Protocel:

  • Bromelain

  • Pancreatin

  • Willard’s Water (to increased absorption of supplements)

  • Shark Liver Oil

  • Germanium-132

Ease of Use and Protocols (Dosage)

Protocel is not all that easy to use for these reasons:

  • Protocel is a liquid and must be shaken and dispensed immediately. Many people do not get a good dose of Protocel because it settles so quickly.

  • You must take a dose every four hours, consistently (you can skip one dose when sleeping.

  • Some people cannot stand the taste, although I think it tastes OK.

  • There are supplements and treatments that cannot be taken while taking Protocel.

People who change their eating habits greatly increase the effectiveness of the supplements they take.


Some people want to continue Protocel after remission. I know of one person who continues to take Protocel five years after his remission; no side effects have been observed. However, if you reduce the dosage size or schedule of Cantron. Protocel WILL NOT WORK as a tumor treatment. However, Protocel is a most powerful antioxidant and can be taken once or twice a day for its antioxidant benefit. Antioxidants are well recognized cancer fighters.

Critical CAT scan Information

As Protocel works and tumors start to break down, they can appear to get larger. CAT scans sometimes can't distinguish between growing tumors and tumors that are breaking down, but a PET scan can verify the breakdown of tumors.

Side Effects and Toxicity

Protocel does not seem to have any side effect except that initially a person may feel tired. On average tiredness lasts 2 1/2 weeks, but some patients report that it lasts longer. This is an indication that Protocel is working. Some people who are having digestion problems may not be able to keep Protocel down. Using simple food combining can reduce digestion problems; do not eat starch with meat, and do not eat fruit with other foods. Another solution is to switch to rectal administration which is explained with the other dosage information.

One woman mistakenly drank an entire bottle of Protocel and only experienced diarrhea the next day. She discovered her mistake and started taking the correct dosage. She is now cured of cancer.

Due to the many changes a woman’s body goes through during pregnancy, Protocel is not recommended during pregnancy just to be on the safe side.

The Toxicity Testing Procedure

Although Sheridan was unable to get a lab to perform a toxicity test on Entelev, one interested group succeeded in getting the test performed by changing the name. This group fears reprisals from the FDA and have requested that I not include the cover-name they used and the date of the test. However, I received permission to publish the results of the test.

Toxicity tests establish the level of a compound at which half the test mice die. The level is expressed in terms of milligrams per kilogram of the animal’s body weight. For example, the toxicity of aspirin is 390mg/kilo; if each mouse weighed a kilogram half of them would die if they were each given 390 mg. The test procedure for new compounds is to slowly increase the level of the compound until half the mice die.

The test lab started the test in the normal way (see above paragraph) and eventually tested levels of hundreds of milligrams per kilo of body weight and no mice died. When the lab got to a level of 5000mg/kilo of body weight they stopped the gradual increments because no mice had yet died. They jumped the level to 11,000 mg per kilo of body weight and finally 70% of the mice died. This level is the equivalent of a 150 pound man taking 700, 1000 mg (“horse”) pills.


Protocel is a delicate treatment whose effect can be stopped by a number of substances. Before continuing with the ordering information, decide if you are willing to avoid taking all of the substances listed below that interfere with Protocel.

Foods to Avoid

Reducing your intake of refined sugar had been known to aid the effects of Protocel. Fructose, honey, and 100% maple syrup are much better.

Vitamins to Avoid

Do not take any supplements that contain the vitamins or supplements listed below.

Vitamin C (taking vitamin C is the number one reason that Protocel fails to work)
Vitamin E
CoEnzyme Q10
Sulfhydrazly antioxidants which includes:
Alpha-lipoic acid

Cesium Chloride and Potassium may cause a problem, but more study is needed before these are definite substances to avoid.

If you are currently taking supplements that contain any of the above, you must decide if you are willing to stop taking them in order to use Protocel most effectively. Naturally occurring quantities in food has not caused any problems. Do not use any information from the Renewal & Wellness web site it is full of dead ends and they do not correct their mistakes. Just use the 800 order number which you will find after reading the Ordering Preliminaries page and the final ordering page on this web site. See Manufacturers for the link to the Ordering Preliminaries page.

Treatments to Avoid

Burdock Root
Essiac and Flor-Essence (which is similar to Essiac with a couple of extra ingredients)
Ozone treatments ( oxygen treatments such as hyperbaric oxygen are beneficial to the functioning of Protocel)
Flax seed oil
IP6 (in theory there may be a problem, but case histories are needed)
714-x some cases indicate that 714-x may interfere with Protocel
Ozone is very counter to Protocel
Hydrogen peroxide
Colloidal silver - the heavy metal quality of silver could cause a reaction with Protocel.
Pau d'arco with Germanium-132 (taking either separately with Cantron is OK)

Treatments that Can Be Taken with Protocel

The following do not interfere with Protocel as far as experience has shown:

Ambrotose (plant saccharides)
B17 ( Laetrile)
Betaine hydrocholoride
Blue Green Algae (believed to have no problems with Protocel, but no case history to verify)
Borage oil
Boron Calcium
Coumadin (an anti-coagulant)
Diuretics in general
Enzymes (generally speaking)
Fish oil (EPA, DHA)
Folic acid
Germanium-132 (helps Protocel)*
Glutamic acid hydrochloride
Grape seed extract
Hormone inhibitors
Hyperbaric oxygen
Interferon (although it is highly toxic)
IP-3 (similar to IP-6, but significantly different)
JuicePlus has about 200 mg of C in a daily dose.
Lemon bioflavonoids
Linolenic acid

Megace (Megestrol Acetate)
Melatonin (occasionally)
Metoprolol tartrate
NONI® Juice
Pantothenic acid
Para-aminobenz acid
Pau d'arco (may help Protocel)*
Polysaccharides are generally compatible
Rice bran
Rose hips (if the level of vitamin C is low)
Saw palmetto
Shark liver oil (Life Extension recommends not longer than one month of treatment)
Secal and Entergenic concentrate
Shiitake Mushrooms
Silica Hydride
Thymic Protein A
Venus Fly Trap

*Taking Germanium-132 and Pau d'arco will interfere with Protocel.

It is generally suggested that herbs be discontinued because it is unknown how they will react with Protocel. Other substances whose reaction with Protocel is currently unknown:

Cat's Claw
Vilcora (Cat's Claw)
IP-6 (may interfere)

Sales de potasio
Mucosolvan (probablly OK)
Salbutamol spray
Bach flowers
Terapia vibracional energética

The above lists were produced with the assistance of Tony Bell, PhD (chemistry).

Chemo with Protocel to Reduce Side Effects

Although chemo prevents Protocel from working, taking Protocel while taking chemo reduces the side effects of chemo, but does not reduce the effectiveness of chemo. For months after chemo treatments, it may be difficult for Protocel to work. Protocel does start right away, but produces results more slowly after taking chemo. Even fairly healthy people can take many months to recover from chemo.

Years Available

Protocel has been widely available in one formulation or another since the early 1980s.

Cost per Month

Depending upon the size ordered, Protocel costs about $75 a month.

PSA Numbers for Prostate Cancer Patients

PAS numbers can escalate for a month or more while taking Protocel. This actually means that Protocel is working.

There are two types of Protocel, 23 and 50. Analysis of the two formulas indicates that the following lists represent the better of the two formulas to start with.

Formula 23

Formula 50

Auto-immune diseases
Bladder cancer
Brain tumors (primary)
Kidney cancer
Multiple melanoma
Prostrate cancer
Wilmes tumor
Autoimmune disorders
Crohn's disease
Multiple sclerosis
Pets with any condition
Viral infections
Weak kidneys

Cervical cancer
Colon cancer
Esophageal cancer
Liver cancer (primary)
Lung cancer
Non-Hodgkin's lymphoma
Ovarian cancer
Pancreatic cancer
Rhabdoid brain tumors
Stomach cancer
Squamous cell cancer
Throat cancer
Uterine cancer




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